Oei SG, Helmerhorst FM, Bloemenkamp KWM, Hollants FAM, Meerpoel DM, KeirseMJNC.
Effectiveness of the postcoital test. BMJ 1998; 317:502-5.
To investigate the impact of the postcoital test on the pregnancy rate among subfertile couples and on the number of other diagnostic tests and treatments.
Randomised controlled study.
A university and two non-university teaching hospitals in the Netherlands.
New couples at infertility clinics, 1 March 1993 to 1 October 1995; randomisation to an intervention group (series of infertility investigations that include the postcoital test) or to a control group (series excluding the test).
MAIN OUTCOME MEASURE:
Cumulative pregnancy rate.
Of 736 consecutive new couples, 444 fulfilled the inclusion criteria and consented to participate (intervention group, 227; control group, 217). Treatment was given more often in the intervention group than in the control group (54% v 41%; difference 13% (95% confidence interval 4% to 22%)). Yet cumulative pregnancy rates at 24 months in the intervention group (49% (42% to 55%)) and the control group (48% (42% to 55%)) were closely similar (difference 1% (-9.0% to 9.0%)).
Routine use of the postcoital test in infertility investigations leads to more tests and treatments but has no significant effect on the pregnancy rate.